The AccuTOF™ LC-Express is the fourth generation of the successful AccuTOF™ LC series, a robust and easy-to-maintain, high-throughput mass spectrometer aiming for high productivity with multiple ionization methods.
JEOL's unique ionization technology, DART™ (Direct Analysis in Real Time) can rapidly provide accurate mass information. It is also easy to replace the ion source with the electrospray ionization (ESI) source for LC/MS operation, or with ColdSpray ionization (CSI) source. Thus, the AccuTOF™ LC-Express can satisfy a variety of research needs in organic chemistry and material science.
You can acquire high mass-resolution, accurate mass spectra in real time by simply presenting samples of various shapes and states to the DART™ ion source without any sample preparation. DART™ can handle samples with arbitrary shapes or "dirty" sample that conventional analytical method cannot deal with.
With the standard electrospray ionization (ESI) source, the AccuTOF™ LC-Express can be used as an LC-MS system. In addition, applications can be expanded by adding an optional atmospheric pressure chemical ionization (APCI) source.
With the optional ColdSpray ionization (CSI) source, thermally labile analytes, including self-assembling supramolecular complexes, some classes of organometallic complexes, and short-chain double stranded DNAs, can all be analyzed intact.
ColdSpray ionization was developed by Prof. Kentaro Yamaguchi, et al., of Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University (previously Chiba University) and the result of a project funded by the Japan Science and Technology Agency (JST).
Easy and quick ion source exchange to support multiple ionization methods
Switching from ESI to DART™ is easy and quick on the AccuTOF™ LC-Express since no additional interface for DART™ needs to be installed due to a high-capacity vacuum pumping system. The combination of AccuTOF™ LC-Express and DART™ ion source is able to detect a wider range of polar and nonpolar compounds than any other DART™ MS system. With no additional interface, there is virtually no carryover from one analysis to another, even for 'dirty' and 'sticky' samples.