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JMS-S3000 SpiralTOF™ series Shared Instrument Applications Notebook

Edition August 2023

This is an application notebook that summaries a wide variety of applications of the JMS-S3000 SpiralTOF™ series MALDI-TOFMS that are useful as a shared instrument at universities.

Please see the PDF file for the additional information.
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Table of Contents

JMS-S3000 SpiralTOF™-plus 2.0 MALDI-TOFMS as a Shared Instrument P1〜

Organic Chemistry P3〜

  • Accurate mass measurement of small molecules:
    Analysis of medicinal properties in a combination cold remedy by using JMS-S3000 "SpiralTOF™" (MSTips No. 241)

  • Accurate mass measurement of a large molecule:
    Measurement of boroxine cage using JMS-S3000 "SpiralTOF™" (MSTips No. 369)

  • Structural analysis of a small molecule:
    Structural analysis of a small molecule using JMS-S3000 "SpiralTOF™-plus 2.0"ーMS/MS measurement of a photodegradation product of reserpineー (MSTips No. 365)

Polymers / Oligomers / Surfactants P9〜

  • Molecular weight distributions of high molecular weight polymers:
    Analysis of high molecular weight polystyrene standards by using JMS-S3000 "SpiralTOF™" with Linear TOF option (MSTips No. 199)

  • Analysis of anionic surfactants in negative ion detection mode:
    Structural analysis of anionic surfactants in MALDI negative ion mode using "SpiralTOF™- plus" (MSTips No. 333)

  • Analysis of an insoluble polymer with solvent-free method:
    Analysis of low molecular weight polyethylene with solvent-free method using JMS-S3000 "SpiralTOF™" (MSTips No. 235)

Proteins / Peptides P15〜

  • Molecular weight measurement of proteins:
    High Sensitivity Analysis of Intact Proteins Using Linear TOF (MSTips No. 227)

  • Identification of a protein with peptide mass fingerprinting (PMF) method:
    Analysis of Bovine Serum Albumin (MSTips No. 166)

  • Identification of a protein with MS/MS ion search method:
    High-Energy CID Analysis of Bovine Serum Albumin (MSTips No. 174)

  • Amino acid sequence analysis of a peptide:
    Structural Analysis of a High Molecular Weight Peptide (MSTips No. 175)

  • Amino acid sequence analysis by using In-source Decay (ISD) method:
    MALDI-ISD Measurements Using Both the SpiralTOF™ Mode and the Linear Mode (MSTips No. 229)

Lipids P25〜

  • Structural analysis of phospholipids:
    Structural analysis of phospholipids in egg yolk using JMS-S3000 "SpiralTOF™" with TOFTOF option (MSTips No. 185)

Nucleic Acids P27〜

  • Accurate mass measurement of a synthetic nucleic acid:
    Analysis of oligonucleotides using JMS-S3000 "SpiralTOF™-plus 2.0" (MSTips No. 364)

Saccharides P29〜

  • Structural analysis of oligosaccharides:
    High-energy CID Mass Spectrometry of Oligosaccharides (MSTips No. 366)

Natural Products P33〜

  • Structural analysis of a natural product:
    Analysis of the Natural Organic Compound YTX by Using the TOF-TOF Option

Mass Spectrometry Imaging P35〜

  • High mass-resolution MS imaging of lipids in a mouse brain section:
    High mass-resolution MS imaging using JMS-S3000 "SpiralTOF™" and statistical data analysis (MSTips No. 370)

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