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AccuTOF™ GC series GCxGC Applications Notebook

Edition February 2026

Over 50 pages of GC×GC applications for petroleum, food, and materials analysis

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Overview

For the past two decades, JEOL has steadily advanced GCxGC (comprehensive two-dimensional gas chromatography) applications. In 2005, our first-generation GC-TOFMS—the JMS-T100GC AccuTOF™ GC—set a milestone by enabling accurate-mass measurements for GCxGC-separated components, achieving 5,000 mass resolution with acquisition speed at 25 spectra per second.
Today, our seventh-generation GC-TOFMS, the JMS-T2000GC AccuTOF™ GC-Alpha 2.0, showcases the dramatic technology gains made since then, delivering 30,000 mass resolution at 50 spectra per second. Further strengthening GCxGC workflows, msFineAnalysis AI Ver. 3 (released August 2025) brings JEOL’s distinctive AI Structural Analysis capability to GCxGC data.
This Applications Notebook highlights a broad range of applications—spanning petroleum and petrochemicals, food, flavor and fragrance, and materials and chemical analysis—acquired using JEOL’s AccuTOF™ GC series of time-of-flight mass spectrometers combined with GCxGC.

Recommended for

  • Researchers seeking real-world GC×GC applications across complex sample types
  • Analysts exploring how GC×GC improves separation compared to 1D-GC
  • Users evaluating GC×GC workflows combined with EI/FI/PI ionization
  • Scientists interested in non-targeted GC×GC analysis with AI structural prediction
  • Professionals comparing GC×GC performance for specific fields (fuels, flavors, polymers)

Table of Contents

Petroleum and Petrochemicals P1〜

  • GCxGC data analysis of msFineAnalysis AI Ver. 3 ①Diesel fuel (MSTips No. 509)
  • GCxGC data analysis of msFineAnalysis AI Ver. 3 ③Pyrolysis oil (MSTips No. 511)
  • Biomarker Analysis in Petroleum Samples Using GC×GC-HRTOFMS with an Ion Source Combining Electron Ionization (EI) and Photo Ionization (PI) (Ubukata, M., Ueda, Y., JEOL news, 53, 54 - 58, 2018)
  • GCxGC TOFMS Analysis of Base Oils with CI, PI, FI (MSTips No. 285)
  • Diesel Fuel Classification Analysis Using GC x GC/FI and Kendrick Mass Defect Plots
  • GC x GC/EI and GC x GC/FI Measurements Using the EI/FI Combination Ion Source (MSTips No. 225)
  • Analysis of diesel oil by using GC x GC-HRTOFMS (FI) with 2 different sets of column combinations (MSTips No. 154)

Food, Flavor, and Fragrance P27〜

  • Non-targeted Analysis of Aroma Compounds in Japanese Curry Roux by GCxGC-TOFMS (MSTips No. 508)
  • SPME-GCxGC/HRTOFMS Analysis of Tequila (MSTips No. 231)
  • Aroma Oil Analysis using GCxGC-HRTOFMS (MSTips No. 194)

Materials and Chemistry P39〜

  • GCxGC data analysis of msFineAnalysis AI Ver. 3 ②Polymer pyrolysis (MSTips No. 510)
  • Identification and distribution analysis of additives in a molded NBR by PY/GCxGC/HRTOFMS (MSTips No. 289)
  • Ion Exchange Resin Analysis by using Pyrolysis-GCxGC-MS (MSTips No. 274)
  • Ethylene Propylene Diene Monomer Rubber Analysis by using Pyrolysis-GCxGC-MS (MSTips No. 273)
  • Natural Polymer Analysis by using Pyrolysis-GCxGC-MS - "Urushi" analysis with GCxGC/EI and GCxGC/PI - (MSTips No. 245)

Contact

For any question or inquiry regarding this Applications Notebook, please contact your local JEOL representative, or use the Product Information Request form on our Global Web Site.

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Related products

JMS-T2000GC AccuTOF™ GC-Alpha 2.0 Gas Chromatograph - Time-of-Flight Mass Spectrometer

msFineAnalysis AI Unknown Compounds Structure Analysis Software

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