Application of MICCS-NMR #3
NM060009E
Reaction pathway analysis of radical addition by 11B NMR
Reaction:
This note treats triethylborane (Et3B)-mediated radical addition to oxime ether, where a borane complex is proposed as a key intermediate. However, its isolation is very difficult using conventional methods.
| Slice No. | 0.5M oximeether | 0.5M Et3B |
| 1-10 | 4.0 | 0.0 |
| 10-20 | 3.0 | 1.0 |
| 20-30 | 2.5 | 1.5 |
| 30-40 | 2.0 | 2.0 |
| 40-50 | 1.5 | 2.5 |
| 50-60 | 1.0 | 3.0 |
| 60-80 | 0.0 | 4.0 |
Spectrometer: JNM-ECA400
Pulse sequence: Single pulse
Accumulation: 32scan
Sample is by courtesy of
Prof. T. Naito, Prof. O. Miyata, and Dr. M. Ueda of Kobe Pharmaceutical University.SEARCH APPLICATIONS
Related Products
Are you a medical professional or personnel engaged in medical care?
No
Please be reminded that these pages are not intended to provide the general public with information about the products.